Oh, the treasures residing within…

I saw this colorful juxtaposition in the December Tech Review. By studying the genetic variations in 3,200 Europeans, and mapping the primary differences in their point mutations (500,000 SNPs) along two axes, a remarkable image of Europe emerges.

To be clear, the graph on the right plots individuals on the x,y axes entirely based on their genes. The color of the points shows where they live, so you can compare the clustering to the map on the left.

Notice how physical barriers, like the water around Italy or the mountains between Spain and France restrict the cross-breeding of peoples, reflected in the accumulated genetic separations over many generations.

And the length of Italy on the right graph suggests less cross-breeding between North and South than geographic distance alone would predict, and in contrast to countries like France (love your neighbor, maybe two).

“The resolution of the genetic map was so precise that the investigators were able to find genetic differences among French, German and Italian-speaking Swiss individuals, with French speakers being more similar to the French, German speakers to Germans and Italian speakers to Italians.” – Research summary from UCLA

I have been fascinated by genetic archaeology, from the early work that derived the migration of groups of people (Roman Empire, Ice Age, etc), and then individuals (I’ll share my genetic migration map below).

17 responses to “Geocoding Genes”

  1. this is really, really great, thanks for sharing!

  2. Hey Doc, you are really TOO SMART for your own good, you
    know that? LOL But we still love you the same. 🙂

    And you know that I’m kiddin’ with you, also – I hope!

    Most interesting History – I think I need to get your autograph
    one day.
    I have a grandson that thinks you walk on water and
    wants to grow up and be just like you. He’s 12 now. I told him
    to go for it. I’d let him…..but he HAD to really study extra hard to
    catch up with you!

    BTW – Our National Voting day is around the corner……who do
    you think will come out on top? Seen in my Contacts ~ Judy

  3. dig the Slovak penetration into southern Italy…

  4. No sooner did I finish reading this same article in TR, I stumbled across this entry (great title by the way). After attending a bunch of where2.0 related conferences over the last few years, it is clear that geography is poised for an extreme makeover, and will now occupy center stage within scientific population based studies.

  5. No surprises, but great to see it confirmed 🙂

  6. I imagine a genetic map of India to be just as interesting and colorful!

  7. Hahaha

    Well, it’s easier to on dates with people you can talk to and when you don’t have to cross oceans.

    What’s interesting about this technique is it gives us a way to look for historical genetic traces from war.

    For instance next week I’ll be in Nuristan, which is anecdotally genetically linked to Alexander the Great’s troops. Phenotypically that’s what they look like… but there are alternative hypotheses.
    en.wikipedia.org/wiki/Nuristani_people

    I’ve noticed a lot of phenotypic variation that’s probably due to wartime occupation. The girl and boy on the left in this photo are possibly a second generation from the Russian occupation. Notice the very un-‘Afghan’ phenotype.

    Phenotypic Variation

  8. instantly reminded of Steve McCurry’s photos – was it Balochistan, Waziristan or Kashmir that has an unusually-high incidence of redheads?

  9. So is there a new paper? From what they show in TR it appears to be the same content as published back in September. That article at least had some links!

  10. Same study, republished. Print is slow. =)

  11. i’d say those swiss really did f*** around alot through history
    they are way out of their borders

  12. Slovakia’s position close to Italy is surprising .. would’ve expected a strong linkage with the Czech Republic and Hungary. Is that an artifact, or is there some basis in reality?

  13. i was wondering the same thing, mikel…

  14. My Aunt is into geneology so I stumbled on the DNA testing. Very interesting, she is getting the entire family to do it. I supposedly have Viking DNA which ironically for its reputation has not had a good survival rate as it is uncommon –and I’m in the US. Wouldn’t it be interesting to to do a study of the rest of the globe against the US. That would show something emerging I think. And to predict if US is no longer drawing immigrants in the future, but people are then leaving the US back to the other continents, what could that look like in the future? I liked what LA Lassie said because you are remarkably smart.

Leave a Reply to LA Lassie Cancel reply

Your email address will not be published. Required fields are marked *