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“We have been unwitting participants in a global gut remodeling experiment over past 100 years.” — Prof Bruce German, UC Davis

David Kyle, Evolve BioSystems at SynBioBeta 2018
• 80% of immune system associated with gut. The gut is the nursery for immune system
• Huge growth in immune disorders in children: Asthma 4x, Allergy 4x, Diabetes 5x
• Breast milk: 15% of its energy not usable by baby – it feeds the microflora in the gut.
• Baby Bif is missing in western babies. Instead, we see opportunistic pathogens, leading to a different pH of stools (5 vs 6 bad). The ph has shifted over 100 years.

2 responses to “Infant Immune Disorders and the Microbiome”

  1. You can B.infantis back to the baby Evidence from 100 years ago…And stool pH (as a proxy) has steadily changed over the past 100 years

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