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by Sarah Ives, Distributed Bio., a startup that does Computational immunology at SynBioBeta today.

“1 in a million vaccines will hit the conserved epitope (the part of the target pathogen that does not evolve and change year after year). This is why you need a new flu vaccine each year. Attempts to hit the conserved epitope fail from overfitting.”

2 responses to “The Physics of Vaccines”

  1. How to focus only on the conserved epitope? Concentration-convervation reward coupling. Inverse dose response. ."If we succeed, it’s the last flu shot you’ll ever need. Should also work with HIV, Zika, even weaponized smallpox"

    Ives against the Mushroom Wall

  2. Thanks for posting. Fascinating!

    I’ve been following vaccine research for 26 years and I would love to see this actual presentation. Is that possible?

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