SGI-DNA Launch

4 responses to “SGI-DNA Launch”

1. 

   jurvetson

   Mar 23, 2013 at 3:38 am

   Here is an earlier subsystem; beakers of A,G,T,C and a conveyor of reaction vessels…SGI-DNA is in the same building as the AgBio derivatives Agracast and Agradis (recently acquired by Monsanto)…In the hallway of the new digs… the DNA medium encodes the message: “bridging the gap between the digital and biological worlds.”
   

   They offer a DNA translator…
   My name is GCTTGATAATTGTAAATAGTTTCCCTATTGTAATGAGCTCGTTGC

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2. 

   scleroplex

   Mar 23, 2013 at 7:44 pm

   🙂

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3. 

   Ramones Karaoke

   Mar 23, 2013 at 10:14 pm

   This goes through insane and right out of the other side. And makes microelectronics look dull, which is a remarkable achievement.

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4. 

   jurvetson

   May 30, 2017 at 5:41 pm

   And now, the The Digital-to-Biological Converter (DBC), or "life printer", just came out in Nature Biotech.

   Opening, by Dan Gibson and the Synthetic Genomics team: "DNA templates, RNA molecules, proteins and viral particles were produced in an automated fashion from digitally transmitted DNA sequences without human intervention."

   Highlights: "First, we synthesized a 1.5-kb DNA fragment encoding GFP."
   "We next synthesized Orencia (abatacept), Lucentis (ranibizumab) and Herceptin (trastuzumab) antibody polypeptides"
   "We next applied the DBC to produce an RNA vaccine and a bacteriophage, both of which have potential as therapeutics for infectious diseases."
   "We also produced functional influenza viral particles (H1N1)"
   "Finally, we fully automated production of the ΦX174 bacteriophage, which has a 5,386-bp genome, on the DBC. The genome sequence was manually designed in silico"
   "with the incorporation of large-scale synthesis technologies, one can envision the DBC being used in industrial settings to enable high- volume production of biologics such as proteins and RNA vaccines."

   Summary release from SGI.

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