Canon PowerShot S100
ƒ/2
5.2 mm
1/30
400

"If you want immortality, do something meaningful with your life." — J.C. Venter (1946-2026)

So many memories… I served on the board of his Synthetic Genomics for over a decade and invested in four of his companies. He was indefatigable and pitched me on his latest new startup just last month.

He was the first to sequence the human genome — his own; he gave me a hardback book of his Y chromosome sequence, the one with the SRY gene that made him male. He made the first synthetic life form, a living organism with a near-minimal genome fabricated by chemical synthesis. President Obama awarded him the National Medal of Science.

Time and time again, he pushed the bounds of what people thought possible, often engaging the cutting edge of Moore’s Law and the Carlson Curve of plummeting gene sequencing and synthesis costs. He even made a desktop DNA printer.

And he had a keen sense of humor and joie de vivre throughout. Like our Zero-g flight pictured above. Here are some more of those moments from 21 years of flickr posts on him.

And more in the SynBioBeta Obit

2 responses to “Genomics pioneer Craig Venter has passed”

  1. Fro example, my snap of Sorcerer II in 2006:
    Sorcerer IIIn this elegant research vessel, Craig Venter set sail around the world to shotgun sequence the millions of viruses and bacteria in every spoonful of seawater. From the first five ocean samples, this team grew the number of known genes on the planet by 10x and the number of genes involved in solar energy conversion by 100x. The ocean microorganisms have evolved over a longer period of time and have pathways that are more efficient than photosynthesis.

    Another discovery: every 200 miles across the open ocean, the microbial genes are up to 85% different. The oceans are not homogenous masses. They consist of myriad uncharted regions of ecological diversity… and the world’s largest genetic database.

    From the collection of digital genomes, we are learning to decode and reprogram the information systems of biology. Like computer hackers, we can leverage a prior library of evolved code, assemblers and subsystems. Many of the radical applications lie outside of medicine.

    At the Venter Institute, Craig Venter and Hamilton Smith are leading the Minimal Genome Project. They take the Mycoplasma genitalium from the human urogenital tract, and strip out 200 unnecessary genes, thereby creating a simple synthetic organism that can self-replicate (at about 300 genes). They plan to layer new functionality on to this artificial genome, by splicing cassettes of novel genes discovered in the oceans for energy conversion from sunlight. These synthetic cells have could be used for a variety of materials or energy applications, for example, to generate biofuels from the sun’s energy.

  2. 🙏. a remarkable loss. His vessel docked in our port not so long ago. It was reassuring and humbling. Hopefully he tutored many.

Leave a Reply

Your email address will not be published. Required fields are marked *