The Regeneration Recipe:
They stumbled on not only one but two recipes for regeneration. Retinoic acid and six-3, a gene known to induce the growth of lenses during embryogenesis, were sufficient to cajole lens cells from the ventral iris PEC. In addition, simply inhibiting the bone morphogenetic protein (BMP) pathway, an important patterning pathway in embryogenesis, gave the same result. In 2005, the couple published their results in Nature: They had grown a lens where none had grown before…. But they met silence from the community most likely to use the findings. “A lot of [scientists studying regenerative medicine] don’t realize the relevance of amphibian limb regeneration to mammalian repair and regeneration. You’ll hear comments like ‘What do amphibians have to do with humans?’ http://www.the-scientist.com/2009/08/1/26/1/#Reference_Anchor
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